Made in Italy

Next Generation
Autologous Bio-Filler
System

PRF Centrifugation Technology combined with Albumin Bio-Filler Processing — A Complete Autologous Regenerative System for Medical Aesthetics.

100% Autologous PRF & Albumin
Natural Volume Formation
Superior Biocompatibility
Optimized for Medi Spas & Clinics
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About REGENGROW

Redefining Regenerative Aesthetics

REGENGROW USA brings the pinnacle of European biomedical engineering to the American aesthetic market. Our Italian-manufactured systems represent the gold standard in autologous regenerative technology.

100% Autologous

Our system uses only the patient's own blood — no synthetic additives, chemicals, or anticoagulants. The purest form of regenerative treatment.

Made in Italy

Precision-engineered and manufactured in Italy by Silfradent, a global leader in regenerative medicine technology since 2003. Not mass-produced in China.

Stem Cell Driven

Unlike standard PRP, our CGF technology captures CD34+ hematopoietic stem cells and a higher concentration of growth factors (VEGF, TGF-β1, PDGF).

Complete System

From centrifugation to bio-filler processing, REGENGROW provides everything your clinic needs for a full autologous regenerative treatment workflow.

Our Technology

The Science Behind REGENGROW

Our proprietary system combines CGF centrifugation technology with Albumin Bio-Filler processing to deliver the most advanced autologous regenerative treatment available.

Concentrated Growth Factors (CGF)

CGF-CD34 is a third-generation autologous blood concentrate produced by the MEDIFUGE centrifuge. Through a proprietary variable-speed centrifugation protocol, CGF creates a dense fibrin matrix containing significantly higher concentrations of growth factors and CD34+ stem cells compared to traditional PRP.

  • Dense Fibrin Matrix — Acts as a biological scaffold, releasing growth factors slowly over 7 to 10 days
  • CD34+ Stem Cells — Hematopoietic stem cells captured through variable-speed microprocessor-controlled centrifugation
  • Growth Factors — High concentration of VEGF, PDGF, TGF-β1 for sustained tissue regeneration
  • Versatile Output — One blood draw provides liquid for microneedling, gel for volumizing, and membranes for healing
PPP Platelet Poor Plasma
CGF Growth Factors + CD34+
RBC Red Blood Cells

Triphasic blood separation via MEDIFUGE

RegenGlow AlbuminPRF Bio-Filler

The RegenGlow system transforms Platelet Poor Plasma (PPP) into a natural, injectable bio-filler through controlled thermal processing. By heating albumin proteins to precisely 75°C, we trigger protein self-assembly (denaturation) that creates a biocompatible gel — a 100% autologous, natural filler.

  • Albumin Gel Formation — Human Serum Albumin (HSA) undergoes controlled denaturation at 75°C to form an injectable gel
  • Natural Bio-Filler — Combined with C-PRF at 1:1 or 2:1 ratio for optimal volume and regenerative properties
  • Zero Foreign Materials — Unlike synthetic fillers, contains only the patient's own proteins and growth factors
  • Dual Action — Provides immediate volume while simultaneously stimulating natural collagen production
PPP Extracted
→
Heat at 75°C
→
Albumin Gel
→
Mix with C-PRF
Feature Standard PRP CGF (REGENGROW)
Generation 1st Generation 3rd Generation
Stem Cells (CD34+) Not captured Captured & concentrated
Fibrin Matrix Loose / weak Dense & robust
Growth Factor Release Hours (rapid release) 7–10 days (sustained)
Centrifugation Constant speed Variable speed (microprocessor)
Growth Factor Concentration Moderate Significantly higher
Versatility Liquid only Liquid, gel & membrane
Additives Required Anticoagulants needed None — 100% autologous
Our System

The MEDIFUGE System

Precision-engineered in Italy, the MEDIFUGE MF200 is the cornerstone of the REGENGROW autologous regenerative system — the world's most advanced benchtop CGF centrifuge.

MEDIFUGE MF200 Centrifuge - Made in Italy
MADE IN ITALY

MEDIFUGE MF200 / APAG

"Real Stem Cell" — Innovative Autologous Plasma Phase Separator

The MEDIFUGE is a microprocessor-controlled centrifuge that uses a proprietary variable-speed protocol to produce Concentrated Growth Factors (CGF) with CD34+ stem cells. Unlike constant-speed centrifuges, the MEDIFUGE's intelligent acceleration and deceleration patterns create the ideal conditions for triphasic blood separation.

Processing Mode
CGF & PRF Protocols
Spin Time
4–6 Minutes
Capacity
Up to 6 Tubes
Technology
Variable Speed Microprocessor
Built-in Feature
UV Sterilization
Origin
Made in Italy by Silfradent

Complete System Includes:

  • MEDIFUGE MF200 Centrifuge
  • Bio-Heat Device (APAG) for albumin gel processing
  • Bio-Cool Unit for C-PRF preservation
  • RegenGlow Processing Kit
  • Disposable tube sets & accessories
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Fabrication Protocol

RegenGlow Bio-Filler Protocol

Our streamlined 6-step protocol enables practitioners to produce a 100% autologous bio-filler in under 20 minutes — right in your clinic.

01

Phlebotomy

Prepare the patient and apply a tourniquet. Using a Butterfly 21G needle with a vacutainer holder, collect blood into white-capped tubes. Ensure tubes are filled appropriately to maintain vacuum pressure.

Balanced, 4–6 tubes
02

Centrifugation

Place the white tubes (balanced) into the MEDIFUGE centrifuge. Select the CGF setting and initiate the variable-speed centrifugation protocol.

CGF Setting 4–6 minutes Balanced rotor required
03

Separation (PPP Removal)

Carefully remove tubes from the centrifuge. Using a 21G to 18G 1.5-inch needle, slowly draw up the upper layer of liquid Platelet-Poor Plasma (PPP) into a syringe. Leave the bottom layer undisturbed.

1.5–2ml PPP per tube
04

Bio-Heating & Cooling

Heater Syringes: Place blue-cap PPP syringes into the Bio-Heat device (APAG) at 75°C for 10 minutes. Cooler Tubes: Place remaining white tubes containing C-PRF into the Bio-Cool unit to prevent clotting.

75°C for 10 min Albumin denaturation
05

Cooling

After heating, the PPP transforms into an Albumin Gel. Allow the gel to cool for 1–2 minutes. Collect the remaining 0.5–1ml of C-PRF from the white tubes.

1–2 min cooling Gel formation complete
06

Final Mixing

Connect the Albumin Gel syringe and C-PRF syringe using a female-female interlock. Mix the contents back and forth at a 1:1 or 2:1 ratio (Albumin:C-PRF) to create the final RegenGlow Bio-Filler. Ready for injection with a 22–25G microcannula needle.

1:1 or 2:1 ratio 22–25G microcannula

Other skin booster products can also be added to the RegenGlow Bio-Filler if desired. The entire protocol takes approximately 15–20 minutes from blood draw to injectable product.

Why REGENGROW

The REGENGROW Advantage

In a market flooded with mass-produced alternatives, REGENGROW stands apart with genuine Italian engineering and proven clinical results.

Made in Italy

Every MEDIFUGE unit is precision-manufactured in Italy by Silfradent, a company with over two decades of expertise in regenerative medicine technology. While competitors rely on mass-produced Chinese manufacturing, REGENGROW delivers European quality, precision, and reliability.

  • Italian precision engineering since 2003
  • Silfradent — global leader in CGF technology
  • Rigorous European quality standards
  • Individual unit calibration & testing

3rd Generation Technology

CGF with CD34+ stem cells represents the most advanced form of autologous blood concentrate — far beyond what standard PRP systems can achieve.

Zero Additives

100% autologous — no synthetic chemicals, no anticoagulants, no foreign materials. The safest possible treatment for your patients.

Complete Workflow

Not just a centrifuge — a complete system including Bio-Heat, Bio-Cool, and all processing components for a seamless clinical workflow.

Sustained Release

Growth factors released over 7–10 days through a dense fibrin matrix, delivering superior and longer-lasting results compared to PRP's rapid release.

Proven Results

Backed by published clinical studies and case series demonstrating significant improvements in skin quality, volume, and overall rejuvenation outcomes.

Clinical Applications

Versatile Treatment Applications

From facial rejuvenation to hair restoration, the REGENGROW system addresses a wide range of aesthetic and dermatological concerns.

Full Face Rejuvenation

Complete facial revitalization improving skin thickness, elasticity, and natural glow through CGF microneedling and AlbuminPRF volumizing.

Natural Volume Restoration

Autologous bio-filler provides natural-looking volume for cheeks, nasolabial folds, temples, and under-eye areas without synthetic materials.

Hair Restoration

CGF with CD34+ stem cells stimulates hair follicles and increases hair density for patients with androgenetic alopecia or alopecia areata.

Scar Treatment

Reduces the appearance of acne scars and promotes organized collagen remodeling for smoother, more even skin texture.

Neck & Décolleté

Addresses fine lines, textural irregularities, and skin laxity in the delicate neck and chest areas where traditional treatments often fall short.

Skin Quality & Anti-Aging

Improves overall skin quality including wrinkles, sagging, stretch marks, dull or dry skin, and hands rejuvenation.

Recommended Treatment Protocol

3–6
Initial Sessions
Every 2–4 weeks
2–4
Maintenance / Year
Sustained results
3–6
Months to Full Results
Continues improving

Ready to Elevate Your Practice?

Join the growing network of clinics and medi spas offering the most advanced autologous regenerative treatments with REGENGROW.

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Get in Touch

Contact REGENGROW USA

Interested in bringing the REGENGROW system to your clinic? Reach out to our team for pricing, demonstrations, and partnership opportunities.

Location

United States

Email

info@regengrowusa.com

Phone

Contact us for details

Our Partners & Credentials

Silfradent Official Partner
Made in Italy European Quality
CGF Pioneer Since 2003